University of California, San Francisco |
Federal guidelines for pre-exposure prophylaxis (PrEP)
The following guidelines from the CDC provide comprehensive information on how to decide when and in whom to start PrEP; what to use; recommended baseline and follow up laboratory and clinical monitoring; and special situations including ambiguous HIV test results and considerations for PrEP use in specific populations.
PrEP Guidelines
2021 PrEP Guidelines from the Centers for Disease Control and Prevention (CDC):
- Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update
Open PDF | From the Centers for Disease Control and Prevention (CDC)
- Clinical Providers’ Supplement: Preexposure Prophylaxis for the Prevention of HIV Infection in the United States – 2021 Update
Open PDF | From the Centers for Disease Control and Prevention (CDC)
Guidance from Previous Years
If you are interested in reading previous years’ CDC guidelines and recommendations pertaining to PrEP and the prevention of new HIV infections, please refer to their online archives.